Digestion is the mechanical and chemical breaking down of food into smaller components, to a form that can be absorbed, for instance, into a blood stream. Digestion is a form of catabolism; a break-down of macro food molecules to smaller ones.
In mammals, food enters the mouth, being chewed by teeth, with chemical processing beginning with chemicals in the saliva from the salivary glands. Then it travels down the esophagus into the stomach, where acid both kills most contaminating microorganisms and begins mechanical break down of some food (eg denaturation of protein), and chemical alteration of some. After some time (typically an hour or two in humans, 4-6 hours in dogs, somewhat shorter duration in house cats, ...), the results go through the small intestine, through the large intestine, and are excreted during defecation.Other organisms use different mechanisms to digest food.
Digestive systems
Digestive systems take many forms. Some organisms, including nearly all spiders, simply secrete biotoxins and digestive chemicals (eg, enzymes)s into the extracellular environment prior to ingestion of the consequent "soup". In others, once potential nutrients or food is inside the organism, digestion can be conducted to a vesicle or a sac-like structure, through a tube, or through several specialized organs aimed at making the absorption of nutrients more efficient.
Invasive digestion
Viruses "digest" through the invasion of cells, thereby reaching "food" held within cells and their vacuoles. Specific viral capsid proteins match receptors on host cell surfaces and are used to fuse the membranes of the virus and the target cell. The cell membrane is then (1) punctured and an opening established, (2) the host cell is induced to endocytose the virus, and the resulting vacuole is either punctured or digested, or (3) some portion of the host plasma membrane, cell wall, or capsule is digested. The viral capsid or genome is injected into the host cell's cytoplasm.
Secretion systems
Main article: SecretionBacteria use several systems to obtain nutrients from other organisms in the environment.
Channel transport system
In a channel transport system several proteins form a contiguous channel traversing the inner and outer membranes of the bacteria. It is a simple system, which consists of only three protein subunits: the ABC protein, membrane fusion protein (MFP), and outer membrane protein (OMP). This secretion system transports various molecules, from ions, drugs, to proteins of various sizes (20 - 900 kDa). The molecules secreted vary in size from the small Escherichia coli peptide colicin V, (10 kDa) to the Pseudomonas fluorescens cell adhesion protein LapA of 900 kDa.
Molecular syringe
A molecular syringe is used through which a bacterium (e.g. certain types of Salmonella , Shigella , Yersinia ) can inject proteins into eukaryotic cells. One such mechanism was first discovered in Y. pestis and showed that toxins could be injected directly from the bacterial cytoplasm into the cytoplasm of its host's cells rather than simply be secreted into the extracellular medium.
Conjugation machinery
The conjugation machinery of some bacteria (and archaeal flagella) is capable of transporting both DNA and proteins. It was discovered in Agrobacterium tumefaciens , which uses this system to introduce the Ti plasmid and proteins into the host which develops the crown gall (tumor). . The VirB complex of Agrobacterium tumefaciens is the prototypic system.
The nitrogen fixing Rhizobia are an interesting case, wherein conjugative elements naturally engage in inter-kingdom conjugation. Such elements as the Agrobacterium Ti or Ri plasmids contain elements that can transfer to plant cells. Transferred genes enter the plant cell nucleus and effectively transform the plant cells into factories for the production of opines, which the bacteria use as carbon and energy sources. Infected plant cells form crown gall or root tumors. The Ti and Ri plasmids are thus endosymbionts of the bacteria, which are in turn endosymbionts (or parasites) of the infected plant.
The Ti and Ri plasmids are themselves conjugative. Ti and Ri transfer between bacteria uses an independent system (the tra , or transfer, operon) from that for inter-kingdom transfer (the vir , or virulence, operon). Such transfer creates virulent strains from previously avirulent Agrobacteria .
Release of outer membrane vesicles
In addition to the use of the multiprotein complexes listed above, Gram-negative bacteria possess another method for release of material: the formation of outer membrane vesicles. Portions of the outer membrane pinch off, forming spherical structures made of a lipid bilayer enclosing periplasmic materials. Vesicles from a number of bacterial species have been found to contain virulence factors, some have immunomodulatory effects, and some can directly adhere to and intoxicate host cells. While release of vesicles has been demonstrated as a general response to stress conditions, the process of loading cargo proteins seems to be selective.
Phagosome
A phagosome is a vacuole formed around a particle absorbed by phagocytosis. The vacuole is formed by the fusion of the cell membrane around the particle. A phagosome is a cellular compartment in which pathogenic microorganisms can be killed and digested. Phagosomes fuse with lysosomes in their maturation process, forming phagolysosomes. In humans, Entamoeba histolytica can phagocytose red blood cells.
Gastrovascular cavity
The gastrovascular cavity functions as a stomach in both digestion and the distribution of nutrients to all parts of the body. Extracellular digestion takes place within this central cavity which is lined with the gastrodermis, the internal layer of epithelium. This cavity has only one opening to the outside that functions as both a mouth and an anus: waste and undigested matter is excreted through the mouth/anus, which can be described as an incomplete gut.
Aboral end Oral end Mouth Oral end Aboral end Exoderm Gastroderm Mesoglea Digestive cavity Medusa (left) and polyp (right)In a plant such as the Venus Flytrap that can make its own food through photosynthesis, it does not eat and digest its prey for the traditional objectives of harvesting energy and carbon, but mines prey primarily for essential nutrients (nitrogen and phosphorus in particular) that are in short supply in its boggy, acidic habitat.
Specialized organs and behaviors
To aid in the digestion of their food animals were created with organs such as beaks, tongues, teeth, a crop, gizzard, and others.
Beaks
Macaws primarily eat seeds, nuts, and fruit, using their impressive beaks to open even the toughest seed. First they scratch a thin line with the sharp point of the beak, then they shear the seed open with the sides of the beak.
The mouth of the squid is equipped with a sharp horny beak mainly made of chitin and cross-linked proteins. It is used to kill and tear prey into manageable pieces. The beak is very robust, but does not contain any minerals, unlike the teeth and jaws of many other organisms, including marine species. The beak is the only indigestible part of the squid.
Tongue
Main article: TongueThe tongue is skeletal muscle on the floor of the mouth that manipulates food for chewing (mastication) and swallowing (deglutition). It is sensitive and kept moist by saliva. The underside of the tongue is covered with a smooth mucous membrane. The tongue is utilised to roll
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