Thyroid function tests ( TFTs ) is a collective term for blood tests used to check the function of the thyroid.

TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy. It is also requested routinely in conditions linked to thyroid disease, such as atrial fibrillation and anxiety disorder.

Panel components

A TFT panel typically includes thyroid-stimulating hormone (TSH, thyrotropin) and thyroxine (T4), and triiodothyronine (T3) depending on local laboratory policy. Thyroid function tests ( TFTs ) is a collective term for blood tests used to check the function of the thyroid.

A TFT panel may include:

  • Circulating concentrations of:
    • Total Hormones
      • thyroid-stimulating hormone (TSH, thyrotropin)
      • thyroxine (T 4 ),
      • triiodothyronine (T 3 )
    • Free hormones (direct measurements)
      • Free T 4
      • Free T 3
    • Carrier proteins
      • Thyroid binding globulin
      • Transthyretin (prealbumin)
      • Albumin
  • Measures of protein binding of thyroid hormones
    • T uptake
    • Thyroid hormone binding ratio (THBR)
    • Thyroxine-binding index (TBI)
  • Calculated indices of free hormones
    • Free T4 index
    • Free T3 index

See also

  • Reference ranges for blood tests#Hormones

References

  1. ^ Dayan CM (February 2001). "Interpretation of thyroid function tests". Lancet 357 (9256): 619–24. doi: 10.1016/S0140-6736(00)04060-5 . PMID 11558500 . http://linkinghub.elsevier.com/retrieve/pii/S0140-6736(00)04060-5 .  

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