PC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla. PC12 cells stop dividing and terminally differentiate when treated with nerve growth factor. This makes PC12 cells useful as a model system for neuronal differentiation.
See also
- Cell culture
- Adrenal medulla
- Cellular differentiation
References
- ^ Greene LA, Tischler AS (July 1976). "Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor". Proc. Natl. Acad. Sci. U.S.A. 73 (7): 2424–8. doi: 10.1073/pnas.73.7.2424 . PMID 1065897.
- ^ "PC-12/CRL-1721 cell line". LGC Promochem: Cell Biology Collection . American Type Culture Collection . http://www.lgcpromochem-atcc.com/common/catalog/numSearch/numResults.cfm?atccNum=CRL-1721 . Retrieved 2008-08-15 .
- ^ Center for Cancer Education
External links
- Wikipedia articles containing the term "PC12 cells"
Calcium Transport Mechanisms of PC12 Cells -- Duman et al. 131 (4 ...
Published online doi:10.1085/jgp.200709915 The Journal of General Physiology, Vol. 131, No. 4, 307-323 The Rockefeller University Press, 0022-1295 $30.00
Proton-Gated Channels in PC12 Cells -- Chu et al. 87 (5): 2555 ...
The Journal of Neurophysiology Vol. 87 No. 5 May 2002, pp. 2555-2561 Copyright ©2002 by the American Physiological Society Proton-Gated Channels in PC12 Cells
pc12 cells definition from the online medical dictionary
Definition of pc12 cells from the online medical dictionary hosted by mondofacto.
PC12 cells - Wikipedia, the free encyclopedia
PC12 is a cell line derived from a pheochromocytoma of the rat adrenal medulla. [1] [2] PC12 cells stop dividing and terminally differentiate when treated with nerve growth factor ...
PC12 (Cytokines & Cells Encyclopedia - COPE)
Cytokines & Cells Online Pathfinder Encyclopaedia ... supports the COPE bioinformatics project with an unrestricted educational grant
Calcium Transport Mechanisms of PC12 Cells
The Journal of General Physiology ARTICLE J. Gen. Physiol. © The Rockefeller University Press $30.00 Volume 131 Number 4 April 2008 307-323 http://www.jgp.org/cgi/doi/10.1085/jgp ...
Analysis of Regulated Secretion Using PC12 Cells | Current Protocols
Abstract Abstract: The catecholamine-secreting PC12 cell line derived from the rat adrenal medulla has long been considered a model system for neurosecretion and neuronal ...
PC12 cells overexpressing tissue plasminogen activator regenerate ...
PC12 cells overexpressing tissue plasminogen activator regenerate neurons to a greater extend and migrate faster than control cells in complex extracellular matrix
Calcium transport mechanisms of PC12 cells.
1: J Gen Physiol. 2008 Apr;131(4):307-23. Epub 2008 Mar 17. Calcium transport mechanisms of PC12 cells. Duman JG, Chen L, Hille B. Department of Physiology and Biophysics ...
L-dopa cytotoxicity to PC12 cells in culture is via its autoxidation.
1: J Neurochem. 1995 Feb;64(2):825-32. L-dopa cytotoxicity to PC12 cells in culture is via its autoxidation. Basma AN, Morris EJ, Nicklas WJ, Geller HM.