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The broken #section links found were: Hydrocodone#Commercial medications containing hydrocodone
This page should not be used as a reference. Please use the main article page instead.Heresay
I removed the following block of text.
"Tolerance to this drug can increase very rapidly if abused. Because of this, addicts often overdose from taking handfulls of pills, in pursuit of the high they experienced very early on in their hydrocodone use."
There are two big problems with this. First, tolerance is not dependent on whether a drug is used as directed or used recreationaly. Tolerence will increase with any long term use. Second, claiming that addicts (condescending) often overdose because they do not calculate how many mg's they are consuming is ridicules for a few reasons. 1. it's easy to divide the dosage needed by the size of the pills to reach the correct number of pills. 2. Taking hand fulls of pills is a lethal dose no matter how tolerent a user is. A hand full could easily have 50 pills in it even with the lowest dosage that is 250mg a lethal dose for all but the the most long term user. Who ever added this also failed to cite a source. Because of all this I could not allow it to remain in the article for even a day waiting for a source. Tomorrow I will replace it with sourced accurate information of acetaminophen and hydrocodone overs dose's. Foolishben 07:24, 28 November 2006 (UTC)
Uncited Fact
I believe drug-related articles should only contain facts cited to specific, reliable sources. Thus, I removed the reference to pharmacological equivalence in the opening paragraph. I also removed the second (and empty) External Links section. --Impaciente 05:24, 11 May 2006 (UTC)
What is the chemical and international names please ?
Yes, that's correct. The smaller number indicates the dose of opioid, in this case hydrocodone, while the larger number represents the dose of the co-drug, in this case, acetaminophen. Lorcet, Lortab, and Vicodin are brand names, all having the same generic active ingredient, the opioid hydrocodone. For example, a prescription for Lortab 5/500mg tablets would represent pills containing 5mg of hydrocodone and 500mg of acetaminophen each. A similar methodology is followed for dosing of other opioid compound drugs, such as Percocet (oxycodone/APAP), which is available in 5/325mg, 10/325mg, and other formulations.
The drug's salt (e.g., bitartrate, hydrochloride, etc.) is listed for the sake of completeness, but should have little or no impact on the consumer of the medication. It primarily represents the true form of the compound as it has been synthesized for consumption and relates to the drug's in vivo solubility and bioavailability.
What are schedules ?The schedules refer to the class of "controlled" substance, I believe.
Proproxyphene in the form of Darvocet (100 of propoxyphene and 650 milligrams of APAP) is actually in Schedule IV status.
Additionally, a dose of hydrocodone (one pill) must be under 15 milligrams and contain the above mentioned non-narcotic analgesics to be placed in the Schedule III category. Anything over 15 milligrams (with or without an added non-opioid)is placed in C-II. It should be noted there is currently no pharmaceutical manufacturer in the United States making hydrocodone tablets with over 15 milligrams of the medicine in it. A physician, however, can write a prescription for a pharmacist to compound hydrocodone tablets with more than 15 milligrams and without the added non-opioid analgesic.
Right. The word "schedule" refers to the US Controlled Substance Act, a policy that calls for careful regulation of drugs with potential abuse. Schedule I drugs are those with no known medicinal value, and includes "street" drugs such as heroin, GHB, Ecstasy, LSD, and others. Schedule II refers to drugs with high abuse potential but with a known medicinal value. Schedule II drugs include the potent, but addictive, opioids such as fentanyl (Duragesic, Actiq), hydromorphone (Dilaudid), morphine (Avinza, MS Contin), oxycodone (OxyContin, Percocet, Percodan); cocaine; methylphenidate (Ritalin); and others, including cocaine (sometimes used in nasal and occular surgery to dilate blood vessels and to numb the area for an operation). Schedule III drugs are those with less abuse potential than those in Schedules I and II, but can still lead to dependence in spite of their medicinal value. Drugs in Schedule III include anabolic steroids, ketamine, paregoric (a opium-derived camphorated tincture), and others. The pattern continues in Schedules IV and V. C-IV are typically drugs in the benzodiazopene category (alprazolam, diazapem, lorazepam and others, plus weaker opioids drugs). C-V's include opioids, such as codeine in the form of cough suppresants (Robitussin-AC), anti-diarrheals (low dose tincture of opoium) and pain medicines in low doses (codeine). Additionally, the new anti-convulsant, Lyrica (pregabalin), which is typically used to treat chronic pain caused by fibromyalgia, diabetic neuropathy pain, spinal cord injury and other forms of chronic pain. It is unique in so much as similar drugs in its class are not typically placed under control substance status.
Deadly dose
Anybody knows what is the deadly dose of Vicodin? 500mg might be a deadly dose.
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Hyrdrocodone (Lortab; Lorcet) comes in 5, 7.5 and 10 mg oral dosages. The 500 mg that you mention is the amount of acetamenophen in combination with the hydrocodone. A 500 mg dose of Lortab would, I'm sure, be deadly to anyone, even the most tolerant addict. Generally the dosages are 5mg/500 mg; 7.5mg/500 mg or 10mg/500 mg in Lortab. The difference with Lorcet is that the mg of acetaminophen is higher, generally 650 mg or 1000 mg. I have been taking Lortab 7.5 for just over 3 years for a chronic pain condition (4 doses per day). At times, I have had to take 2 pills instead of 1, which meant I had to skip a dose later that day or the next. I am tolerant to the medication now so do not get the euphoric effect, even if I take 2 at a time. However, I am quite certain that if I took 66 2/3 7.5 mg pills (the equivilant of 500 mg), I would die.
My only source for this information is my personal experience and what I read on the prescription bottles and the paperwork that comes with my prescriptions. I used to used CVS pharmacy, but now use Fred's. Both places are very good about answering questions about the medications I have to take - believe me, I've annoyed the heck out of the pharmacists - I have OCD and I ask millions of questions about everything.
With all due respect to the above poster, it is not inconceivable for a person to have a tolerance that would allow them to take 500 milligrams of hydrocodone. I have been on OxyContin and another oxycodone medication for over four years for a chronic pain condition. At one point, I was taking 400 milligrams of OxyContin a day, with an additional 150mg of OxyIR, which comes to 550 milligrams. As any person with some knowledge of opioids would tell you, oxycodone is about 2-3 times stronger than hydrocodone. So, yes, a person who has little to no tolerance to narcotics would certainly die of respiratory arrest on 500 milligrams of hydrocodone. But if someone who had a high tolerance to opioids, they could easily take that much hydrocodone. What would kill them, however, is taking that much hydrocodone in a form such as Lortab, Vicodin or Norco, which also has Tylenol in it. These drugs have from 325 to over 700 milligrams of paracetemol in them. Most sources say a person should not take over 4,000 milligrams of it in a 24 hour period. So, in order to consume 500 milligrams of hydrocodone for anyone taking something like Norco (325mg of APAP), they would also ingest 16,250 milligrams of APAP, which would cause permanent damage to the liver. So if someone could safely ingest 500 milligrams of hydrocodone due to their tolerance, they would have to do so with a form that contained little to no paracetemol to safely do it.
With all due respect to the above
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